Ratgif (Cholecalciferol) Toksisiteit By Perde

2025 Outeur: Daisy Haig | [email protected]. Laas verander: 2025-01-13 07:17

Cholecalciferol Vergiftiging in perde

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Cholicalciferol (vitamien D3) is die aktiewe bestanddeel in baie soorte rotgif. 'N Hoë dosis cholicalciferol sal kalsium in die liggaam destabiliseer, wat lei tot 'n toestand van hiperkalsemie en uiteindelik verkalking van die weefsels en organe van die liggaam veroorsaak. Verhoogde vlakke van kalsium in die bloed kan ernstige nierbeskadiging veroorsaak.

Soms sal perde in aanraking kom met perdevoer wat met cholicalciferol besmet is, miskien as die

Simptome

• Verlies van eetlus (anorexia)
• Gewigsverlies
• Depressie
• Moeilike asemhaling (dispnee)
• Oormatige dors (polydipsie) met verhoogde verbruik van water
• Verhoogde produksie van urine (poliurie)
• Swakheid
• Verhoogde hartklop
• Styfheid van die ledemaat
• Resumbency
• Dood

Oorsake

• Inname van cholicalciferol, gewoonlik per ongeluk
• Dit hou gewoonlik besoedeling van voedsel met ro.gif" />

Diagnose

U veearts kan toksisiteit van cholicalciferol diagnoseer deur 'n bloedmonster by 'n laboratorium in te dien wat die serumvlakke van die verbinding sal meet. Meer roetine bloedwerk sal verhoogde vlakke van fosfor en kalsium sowel as tekens van nierbeskadiging toon.

Behandeling

Behandeling vir vergiftiging deur cholialciferol sal van geval tot geval wissel, afhangende van die hoeveelheid

Die algemeenste benadering tot behandeling hou gewoonlik verband met die beperking van die hoeveelheid vitamien D wat deur voedsel en aanvullings ingeneem word. Daar kan 'n kalsiumchelator gegee word, aangesien dit die dermabsorpsie van kalsium sal verminder. Behandeling moet ook begin word vir nierversaking. Dit is gewoonlik ondersteunende sorg en benodig toediening van groot hoeveelhede IV vloeistowwe.

Woon en bestuur

Die herstel van hierdie toksisose kan lank wees en dikwels onbeloon, aangesien verkalking van weefsels en nierversaking nie omgekeer kan word nie. Die prognose word bewaak en genadedood word dikwels verkies.

Voorkoming

Alhoewel toevallige inname nie voorkom kan word nie, kom hierdie tipe toksisisasie soms voor deur die wanbestuur van vitamienaanvullings. Voordat u perd met enige aanvulling begin, moet u dit met u veearts bespreek.